Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | ICOSLG | ||||||||||
| Synonyms | B7-H2 | B7h | B7H2 | B7RP-1 | B7RP1 | CD275 | GL50 | ICOS-L | ICOSL | IMD119 | LICOS | ||||||||||
| Gene Description | ICOSLG, inducible T cell costimulator ligand, encodes a member of the B7 family of ligands, which triggers T cell proliferation and cytokine production upon binding to the T cell receptor, ICOS (PMID: 11973139, PMID: 10549624). Expression of ICOSLG has been identified in myeloma and acute myeloid leukemia (PMID: 19188146, PMID: 16115907), and overexpression of ICOSLG has been observed in esophageal squamous cell carcinoma (PMID: 29147607). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
