USP22 - Gene Detail
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| Gene Symbol | USP22 | ||||||||||||
| Synonyms | USP3L | ||||||||||||
| Gene Description | USP22, ubiquitin specific peptidase 22, encodes the catalytic unit of the deubiquitylase module of the SAGA coactivator complex that regulates transcription initiation (PMID: 34155658, PMID: 18206973), and plays a role in apoptosis (PMID: 34155658), telomere maintenance (PMID: 19683498), cell cycle control (PMID: 18206973), and proliferation (PMID: 21779003). Increased expression of Usp22 has been observed in various tumor types (PMID: 25111486), including breast cancer (PMID: 32494025), neuroblastoma (PMID: 32216173), gastric cancer (PMID: 31689236), and osteosarcoma (PMID: 27983930). | ||||||||||||
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