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Gene Symbol | DICER1 | ||||||||||
Synonyms | aviD | DCR1 | Dicer | Dicer1e | GLOW | HERNA | K12H4.8-LIKE | MNG1 | RMSE2 | ||||||||||
Gene Description | DICER1, endoribonuclease Dicer, plays a role in synthesis of micro-RNA's and in cell proliferation (PMID: 26033159). Somatic loss of function mutations in Dicer1 have been linked to a variety of cancers (PMID: 25176334) including, endometrial (PMID: 26033159), pleuropulmonary blastoma (PPB), cystic nephroma (CN), and Sertoli-Leydig cell tumor (SLCT) (PMID: 27906793). | ||||||||||
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