Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol FOLH1
Synonyms FGCP | FOLH | GCP2 | GCPII | mGCP | NAALAD1 | PSM | PSMA
Gene Description FOLH1, folate hydrolase 1, encodes prostate-specific membrane antigen (PSMA), which is a type II transmembrane protein that acts as a glutamate carboxypeptidase resulting in folate hydrolase activity as well as NAALADase activity (PMID: 9816319, PMID: 8570628). Overexpression of FOLH1 (PSMA) has been observed in prostate cancer (PMID: 16985927), lung cancer (PMID: 25978404), and metastatic breast cancer (PMID: 29426963).
Additional content available in CKB BOOST