Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PHF19
Synonyms MTF2L1 | PCL3 | TDRD19B
Gene Description PHF19, PHD finger protein 19, encodes a member of the polycomb-like family of proteins that is involved in chromatin organization and plays a role in regulation of embryonic stem cell self-renewal by recruiting the polycomb repressive complex 2 to stem cell genes, which leads to suppression of transcription (PMID: 23104054, PMID: 23160351). Phf19 overexpression has been observed in hepatocellular carcinoma, glioblastoma and multiple myeloma (PMID: 25955388, PMID: 30323224, PMID: 31383640).
Additional content available in CKB BOOST