GATA4: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

GATA4

Synonyms

ASD2 | TACHD | TOF | VSD1

Gene Description

GATA4, GATA binding protein 4, encodes a zinc-finger type transcription factor that plays a role in development of the heart (PMID: 29111206), and multiple endoderm derived organs including liver and pancreas (PMID: 19028990, PMID: 16079152). Gata4 hypermethylation has been identified in multiple tumor types including ovarian cancer (PMID: 28241454), gastric carcinoma (PMID: 20222162), and glioblastoma (PMID: 23320456), and overexpression has been identified in pancreatic ductal adenocarcinoma (PMID: 19918328).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
2626	8	8p23.1	NM_002052	Unknown

Additional content available in

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Gene Variants 6
Category Variants 1
Molecular Profiles 6
Evidence 0
Clinical Trials 0

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GATA4 - Gene Detail

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