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Gene Symbol ABL2
Synonyms ABLL | ARG
Gene Description ABL2, ABL proto-oncogene 2, non-receptor tyrosine kinase, serves as a liaison between extracellular stimuli and signaling pathways involved in cell growth, survival, and invasion (PMID: 23842646). ABL2 amplification, fusions, and altered expression has been observed in a variety of tumor types, including hepatocellular carcinoma (PMID: 24940071), leukemia (PMID: 25098428), and gastric cancer (PMID: 29767389).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
27 1 1q25.2 NM_007314 Oncogene (PMID: 30606230)
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