Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | GLI2 | ||||||||||
| Synonyms | CJS | HPE9 | PHS2 | THP1 | THP2 | ||||||||||
| Gene Description | GLI2, GLI family zinc finger 2, is a transcription factor acting in the Sonic Hedgehog signaling pathway of developmental regulation and is also induced by TGF-beta independently of hedgehog (PMID: 21862631). Crosstalk from hedgehog and TGF-beta may create a cycle that amplifies GLI2-dependent metastasis (PMID: 21862631) and a FHL2-GLI2 fusion has been reported in sclerosing stromal tumors of the ovary (PMID: 31896750). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
