Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol GNAO1
Synonyms DEE17 | EIEE17 | G-ALPHA-o | GNAO | HG1G | HLA-DQB1 | NEDIM
Gene Description GNAO1, G protein subunit alpha o1, is a subunit of the heterotrimeric G protein, which plays a role in transducing cellular signals (PMID: 24366063). Hypermethylation of GNAO1 and subsequent down regulation of expression may play a role in promoting tumorigenesis in hepatocellular carcinoma (PMID: 29709639, PMID: 23984917), however in gastric cancer, overexpression of Gnao1 may correlate with poor prognosis (PMID: 24366063).
Additional content available in CKB BOOST