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| Gene Symbol | ANPEP | ||||||||||
| Synonyms | AP-M | AP-N | APN | CD13 | GP150 | hAPN | LAP1 | P150 | PEPN | ||||||||||
| Gene Description | ANPEP, alanyl aminopeptidase, membrane, is a membrane-bound metalloproteinase that preferentially cleaves neutral amino acids of biologically active peptides (PMID: 18603472), and has non-enzymatic functions in diverse biological processes including phagocytosis (PMID: 24063007), cell polarity (PMID: 34349123), integrin recycling and cell migration (PMID: 31040262), angiogenesis (PMID: 11157481), and viral infection (PMID: 1350662). Increased expression of ANPEP has been observed in pancreatic cancer (PMID: 27788483), non-small cell lung cancer (PMID: 16361553), and hepatocellular carcinoma (PMID: 29145632). | ||||||||||
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