Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol GSK3B
Synonyms
Gene Description GSK3B, glycogen synthase kinase 3 beta, is a serine-threonine kinase that is involved in glycogen synthesis, regulates proteosomal degradation of signaling molecules including beta-catenin, Ccnd1, Myc, and Jun (PMID: 11563964, PMID: 29379583), and also promotes cell survival through activation of NF-kappaB signaling (PMID: 28053024). GSK3B overexpression has been identified in pancreatic and colorectal cancer (PMID: 22100174, PMID: 16043125).
Additional content available in CKB BOOST