Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene Symbol | GUCY2C | ||||||||||
Synonyms | DIAR6 | GC-C | GCC | GUC2C | HSER | MECIL | MUCIL | STAR | ||||||||||
Gene Description | GUCY2C, guanylate cyclase 2C, is a heat-stable enterotoxin receptor that binds guanylin and uroguanylin and is expressed in the intestinal epithelium (PMID: 28162021, PMID: 29210639). Aberrant expression of Gucy2c has been observed in colorectal cancer (PMID: 28162021), where it may function as an intestinal tumor suppressor (PMID: 29210639). | ||||||||||
|