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Gene Symbol TLX3
Synonyms HOX11L2 | RNX
Gene Description TLX3, T cell leukemia homeobox 3, is a homeobox-containing transcription factor that plays a role in specification of neuronal subtypes (PMID: 26258652, PMID: 33996801). TLX3 overexpression (PMID: 35562412, PMID: 35385357) and rearrangements are associated with T-cell acute lymphoblastic leukemia (PMID: 15334547, PMID: 18185524, PMID: 34440292).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
30012 5 5q35.1 NM_021025 Oncogene (PMID: 30606230)
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