Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol H1-4
Synonyms dJ221C16.5 | H1.4 | H1E | H1F4 | H1s-4 | HIST1H1E | RMNS
Gene Description H1-4, H1.4 linker histone, cluster member, encodes a member of the histone H1 family, which binds to nucleosomes and plays a key role in chromatin organization (PMID: 23945933, PMID: 19059319) and transcriptional activation of target genes (PMID: 22465951, PMID: 33238524 ). Mutations in H1-4 have been identified in follicular lymphoma (PMID: 24435047, PMID: 24362818) and myeloma (PMID: 27235425).
Additional content available in CKB BOOST