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Gene Detail

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Gene Symbol H1-5
Synonyms H1 | H1.5 | H1B | H1F5 | H1s-3 | HIST1H1B
Gene Description H1-5, H1.5 linker histone, cluster member, encodes a member of the histone H1 family, which binds to nucleosomes and plays a key role in chromatin organization (PMID: 23945933, PMID: 19059319) and transcriptional regulation of target genes (PMID: 21654845). Mutations in H1-5 have been identified in follicular lymphoma (PMID: 24435047) and decreased expression of H1-5 has been identified in ovarian granulosa cell tumors (PMID: 25023763).
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