H3-3B - Gene Detail
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| Gene Symbol | H3-3B | ||||||||||||
| Synonyms | BRYLIB2 | H3.3B | H3F3B | ||||||||||||
| Gene Description | H3-3B, H3 histone family member 3B, encodes the H3.3 histone variant, which is a component of the nucleosome, and plays a role in transcriptional regulation and genomic stability (PMID: 27894815, PMID: 25773741). H3-3B mutations have been associated with chondroblastoma, and have been identified in clear-cell chondrosarcoma and osteosarcoma (PMID: 24162739). | ||||||||||||
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