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| Gene Symbol | HFE | ||||||||||
| Synonyms | HFE1 | HH | HLA-H | MVCD7 | TFQTL2 | ||||||||||
| Gene Description | HFE, homeostatic iron regulator, modulates iron uptake through an interaction with Tfr1 and plays a role in iron homeostasis (PMID: 26456104, PMID: 28474781) and as a potential regulator of T lymphocyte activation (PMID: 28474781). HFE mutations may be associated with increased risk of colorectal cancer (PMID: 2099304, PMID: 12529348, PMID: 23553028). | ||||||||||
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