HLA-DQB1 - Gene Detail
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| Gene Symbol | HLA-DQB1 | ||||||||||||
| Synonyms | CELIAC1 | HLA-DQB | IDDM1 | ||||||||||||
| Gene Description | HLA-DQB1, major histocompatibility complex, class II, DQ beta 1, encodes a component of the human leukocyte antigen class II histocompatibility complex, which is involved in the presentation of antigens to the immune system (PMID: 19412418, PMID: 37201029) and may play a role in autoimmunity (PMID: 37201029). Decreased expression of HLA-DQB1 has been observed in lung adenocarcinoma (PMID: 31114327) and altered HLA-DQB1 allele frequencies have been observed in breast cancer (PMID: 21720852), cervical carcinoma (PMID: 18650831), and gastric adenocarcinoma (PMID: 8690208). | ||||||||||||
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