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HOXA9 - Gene Detail

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Gene Symbol HOXA9
Synonyms ABD-B | HOX1 | HOX1.7 | HOX1G
Gene Description HOXA9, homeobox protein Hox-A9, is a homeodomain-containing transcription factor that regulates transcriptional activation and repression (PMID: 27258906) and plays a role in hematopoiesis (PMID: 27258906) through regulation by MLL histone methytransferase (PMID: 27258906). Overexpression of Hoxa9 has been commonly observed in acute myeloid leukemia and is associated with poor prognosis (PMID: 30270123, PMID: 26028034).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
3205 7 7p15.2 NM_152739 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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