HOXA9: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

HOXA9

Synonyms

ABD-B | HOX1 | HOX1.7 | HOX1G

Gene Description

HOXA9, homeobox protein Hox-A9, is a homeodomain-containing transcription factor that regulates transcriptional activation and repression (PMID: 27258906) and plays a role in hematopoiesis (PMID: 27258906) through regulation by MLL histone methytransferase (PMID: 27258906). Overexpression of Hoxa9 has been commonly observed in acute myeloid leukemia and is associated with poor prognosis (PMID: 30270123, PMID: 26028034).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
3205	7	7p15.2	NM_152739	Both: Oncogene and Tumor suppressor (PMID: 30606230)

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Gene Variants 4
Category Variants 1
Molecular Profiles 2
Evidence 2
Clinical Trials 1

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HOXA9 - Gene Detail

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