Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol HPCAL1
Synonyms BDR1 | HLP2 | VILIP-3
Gene Description HPCAL1, hippocalcin like 1, encodes a neuronal calcium sensor protein (PMID: 27820860) involved in calcium binding and myristoylation thereby potentially leading to regulation of various cellular signaling pathways (PMID: 12445467), including the MAPK pathway (PMID: 12445467, PMID: 18989702). Decreased expression of HPCAL1 has been identified in hepatocellular carcinoma (PMID: 26659654), while increased expression has been observed in glioblastoma (PMID: 30843345), and a fusion with ALK has been identified in non-small cell lung cancer (PMID: 32523354).
Additional content available in CKB BOOST