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HRG - Gene Detail

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Gene Symbol HRG
Synonyms HPRG | HRGP | THPH11
Gene Description HRG, histidine rich glycoprotein, is a glycoprotein synthesized in the liver that circulates in the plasma and binds heme and divalent metal ions and plays a role in angiogenesis, coagulation, fibrinolysis, apoptosis, cell adhesion, cell migration, cell growth, cell proliferation, and the immune response (PMID: 26336134, PMID: 24510988). Decreased expression of Hrg has been observed in endometrial carcinoma (PMID: 21489304) and ovarian cancer (PMID: 22827608).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
3273 3 3q27.3 NM_000412 Unknown
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