Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol HES1
Synonyms bHLHb39 | HES-1 | HHL | HRY
Gene Description HES1, hes family bHLH transcription factor 1, is a transcriptional repressor of genes that require a bHLH protein for their transcription and is a downstream target of Notch signaling and plays a role in T-cell development (PMID: 27066918). Hes1 overexpression has been observed in a variety of solid tumor types (PMID: 25139105; PMID: 25234168; PMID: 24492635, PMID: 27066918).
Additional content available in CKB BOOST