Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol BIRC3
Synonyms AIP1 | API2 | c-IAP2 | CIAP2 | HAIP1 | HIAP1 | IAP-1 | MALT2 | MIHC | RNF49
Gene Description BIRC3, baculoviral IAP repeat containing 3, is a member of the inhibitors of apoptotic protein (IAP) family that regulates apoptosis and other cellular processes through ubiquitination of targeting proteins (PMID: 23790005). BIRC3 mutations are frequently identified in hematological cancers (PMID: 17692804, PMID: 21881048, PMID: 24145436), including chronic lymphocytic leukemia (PMID: 31371416).
Additional content available in CKB BOOST