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DNAJB1 - Gene Detail

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Gene Symbol DNAJB1
Synonyms Hdj1 | Hsp40 | HSPF1 | RSPH16B | Sis1
Gene Description DNAJB1, DnaJ heat shock protein family (Hsp40) member B1, encodes a molecular chaperone of the DnaJ/Hsp40 family, which stimulates the ATPase activity of Hsp70 proteins, and plays a role in protein folding and degradation (PMID: 16952052, PMID: 20651708). A DNAJB1-PRKCA fusion has been associated with fibrolamellar hepatocellular carcinoma (PMID: 29162699, PMID: 24578576).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
3337 19 19p13.12 NM_006145 Unknown
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