Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol IGF2
Synonyms C11orf43 | GRDF | IGF-II | PP9974 | SRS3
Gene Description IGF2, insulin like growth factor 2, encodes for a growth factor involved in cell growth and differentiation processes that occur during embyronic development and adult life (PMID: 18308616). Overexpression of IGF2 has been linked to mesenchymal tumors and hepatocellular carcinoma and may be associated with worse prognosis in breast cancer, esophageal cancer, chronic myeloid leukemia (PMID: 24080445), colorectal cancer (PMID: 31623387), and adrenocortical carcinoma (PMID: 31378849).
Additional content available in CKB BOOST