Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol IGFBP1
Synonyms AFBP | hIGFBP-1 | IBP1 | IGF-BP25 | PP12
Gene Description IGFBP1, insulin-like growth factor binding protein 1, is a member of the IGF-binding protein (IGFBP) family that is mainly expressed by the liver and circulates in the plasma to regulate cell migration and survival (PMID: 27152521). Aberrant expression of Igfbp1 has been observed in colorectal cancer liver metastasis (PMID: 27152521) and in endometrial cancer (PMID: 26802879).
Additional content available in CKB BOOST