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Gene Symbol FAS
Synonyms ALPS1A | APO-1 | APT1 | CD95 | FAS1 | FASTM | TNFRSF6
Gene Description FAS, Fas cell surface death receptor, is a member of the tumor necrosis factor family of receptors and plays an important role in programed cell death (PMID: 12040174, PMID: 11048730). Mutations in FAS have been identified in non-Hodgkin lymphoma (PMID: 9787134), and altered expression has been identified in solid tumors including colorectal cancer (PMID: 28766682), and breast cancer (PMID: 28121628).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
355 10 10q23.31 NM_000043 Tumor suppressor (PMID: 30606230)
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