Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | IL6R | ||||||||||
| Synonyms | CD126 | gp80 | HIES5 | IL-1Ra | IL-6R | IL-6R-1 | IL-6RA | IL6Q | IL6QTL | IL6RA | IL6RQ | ||||||||||
| Gene Description | IL6R, interleukin 6 receptor, encodes for a receptor, which once bound by IL6, plays a role in anti-inflammation and regeneration via activation of the JAK/STAT, ERK, and PI3K signaling pathways (PMID: 21296109). IL6R signaling has been linked to ovarian carcinoma and lung adenocarcinoma via cross-talk with EGFR, and IL6R expression levels have been correlated to a worse prognosis in prostate cancer (PMID: 21156962). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
