Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol EIF3E
Synonyms eIF3-p46 | EIF3-P48 | EIF3S6 | INT6
Gene Description EIF3E, eukaryotic translation initiation factor 3 subunit E, is part of the translation initiation complex (PMID: 25450521) and impacts a number of cellular functions, including the cell cycle, translation, protein degradation, and DNA repair (PMID: 27814599). An EIF3E-RSPO2 fusion has been identified in colorectal cancer (PMID: 30916365).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
3646 8 8q23.1 NM_001568 Tumor suppressor (PMID: 30606230)
Additional content available in CKB BOOST