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Gene Symbol AR
Synonyms AIS | AR8 | DHTR | HUMARA | HYSP1 | KD | NR3C4 | SBMA | SMAX1 | TFM
Gene Description AR, androgen receptor, belongs to the nuclear hormone receptor family and acts as a transcription factor to regulate transcription or repression of specific genes (PMID: 24909511, PMID: 21784131). AR overexpression leads to ligand independent activation of AR and is common in prostate cancer (PMID: 16598769) and AR mutations and constitutively active splice variants are also commonly observed in prostate cancer (PMID: 31868960).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
367 X Xq12 NM_000044 Oncogene (PMID: 30606230)
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