Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol AR
Synonyms AIS | AR8 | DHTR | HUMARA | HYSP1 | KD | NR3C4 | SBMA | SMAX1 | TFM
Gene Description AR, androgen receptor, belongs to the nuclear hormone receptor family and acts as a transcription factor to regulate transcription or repression of specific genes (PMID: 24909511, PMID: 21784131). AR overexpression leads to ligand independent activation of AR and is common in prostate cancer (PMID: 16598769) and AR mutations and constitutively active splice variants are also commonly observed in prostate cancer (PMID: 31868960).
Additional content available in CKB BOOST