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Gene Symbol ITGA5
Synonyms CD49e | FNRA | VLA-5 | VLA5A
Gene Description ITGA5, integrin subunit alpha 5, interacts with ITGB1 to form a fibronectin receptor and functions in cell adhesion and signaling (PMID: 33408483). Overexpression of Itga5 has been observed to correlate with metastasis in non-small cell lung cancer (PMID: 27143927) and esophageal squamous cell carcinoma (PMID: 26772401).
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