Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ARAF
Synonyms A-RAF | ARAF1 | PKS2 | RAFA1
Gene Description ARAF, A-Raf proto-oncogene, serine/threonine kinase, is a member of the Raf family of serine/threonine protein kinases, which plays a role in cell proliferation and growth (PMID: 17535970). ARAF mutations have been observed in lung adenocarcinoma (PMID: 24569458) and intrahepatic cholangiocarcinoma (PMID: 25608663).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
369 X Xp11.3 NM_001654 Oncogene (PMID: 30606230)
Additional content available in CKB BOOST