Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ITPR2
Synonyms ANHD | CFAP48 | INSP3R2 | IP3R2
Gene Description ITPR2, inositol 1,4,5-trisphosphate receptor type 2, regulates intracellular Ca2+ release (PMID: 25499268) and plays a role in the cell cycle and proliferation (PMID: 25779662). An in-frame fusion of the ETV6 promoter with the C-terminal portion of Itpr2 has been observed in breast cancer (PMID: 20033038) and overexpression of Itpr2 has been observed in AML (PMID: 25779662).
Additional content available in CKB BOOST