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RHOA - Gene Detail

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Gene Symbol RHOA
Synonyms ARH12 | ARHA | EDFAOB | RHO12 | RHOH12
Gene Description RHOA, ras homolog family member A, is a Rho small GTPase that is involved in regulation of actin cytoskeleton dynamics, cell migration, and cell-cycle progression (PMID: 19327386, PMID: 24467208, PMID: 26103434). RHOA mutations are recurrent in diffuse-type gastric cancer and subtypes of lymphomas (PMID: 27693615, PMID: 26103434, PMID: 27991930).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
387 3 3p21.31 NM_001664 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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