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Gene Detail

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Gene Symbol LLGL2
Synonyms HGL | Hugl-2 | LGL2
Gene Description LLGL2, LLGL scribble cell polarity complex component 2, is a scaffold protein that plays a role in ensuring the correct organization and orientation of bipolar spindles for normal cell division (PMID: 30996345). LLGL2 expression is associated with tumorgenesis (PMID: 22580609; PMID: 23110097) and overexpression has been observed in estrogen receptor positive breast cancer (PMID: 30996345).
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