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LPP - Gene Detail

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Gene Symbol LPP
Synonyms
Gene Description LPP, LIM domain containing preferred translocation partner in lipoma, encodes an actin-binding protein involved in cytoskeletal organization and formation of cell-cell junctions (PMID: 16613855, PMID: 18413140) that plays a role in signal transduction and regulation of cell migration and invasion (PMID: 26945059, PMID: 28436416). LPP fusions have been identified in lipoma (PMID: 8812423), pulmonary chondroid hamartoma (PMID: 11066083), acute myeloid leukemia (PMID: 11433529), and lymphoma (PMID: 34381423).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
4026 3 3q27.3-q28 NM_001375462 Oncogene (PMID: 30606230)
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