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Gene Symbol ARNT
Synonyms ARNT1 | bHLHe2 | HIF-1-beta | HIF-1beta | HIF1-beta | HIF1B | HIF1BETA | TANGO
Gene Description ARNT, aryl hydrocarbon receptor nuclear translocator, also known as HIF1-beta, is a common binding partner for Hif1a and Ahr (PMID: 24849811). ETV6-ARNT fusions have been identified in childhood T-lymphoblastic leukemia and acute myeloblastic leukemia (PMID: 20804916, PMID: 10829078, PMID: 24469860, PMID: 30209392) and overexpression of Arnt has been observed in melanoma (PMID: 31741768).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
405 1 1q21.3 NM_001668 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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