LYL1 - Gene Detail
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| Gene Symbol | LYL1 | ||||||||||||
| Synonyms | bHLHa18 | ||||||||||||
| Gene Description | LYL1, LYL1 basic helix-loop-helix family member, plays a role in fetal and adult hematopoietic stem cell function (PMID: 16514064, PMID: 19200805, PMID: 42174007), lymphoid lineage specification (PMID: 22772404, PMID: 42174007), and T-cell progenitor maintenance (PMID: 22772404). A TRB::LYL1 fusion, corresponding to t(7:19), has been identified in acute lymphoblastic leukemia (PMID: 3162254), and LYL1 amplification has been observed in uterine corpus endometrial cancer (PMID: 29716549). | ||||||||||||
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