Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | MC1R | ||||||||||
| Synonyms | CMM5 | MSH-R | SHEP2 | ||||||||||
| Gene Description | MC1R, melanocortin 1 receptor, is a G protein-coupled receptor that binds to alpha-MSH and ACTH and regulates pigment production, and also plays a role in response to UV radiation and DNA repair (PMID: 24807163, PMID: 29622793, PMID: 34362555). MC1R variants have been associated with an increased risk for melanoma (PMID: 11500805, PMID: 20876876, PMID: 32898390). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
