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Gene Symbol AFDN
Synonyms AF6 | l-afadin | MLL-AF6 | MLLT4
Gene Description AFDN, afadin, adherens junction formation factor, encodes Afadin, which has roles in cell adhesion, migration, survival, and differentiation (PMID: 23481206). AFDN is a frequent binding partner for MLL in acute leukemia (PMID: 30203571) and loss of Afdn expression is associated with poor prognosis in breast cancer (PMID: 20395419, PMID: 21478912).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
4301 6 6q27 NM_001366320 Oncogene (PMID: 30606230)
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