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Gene Symbol | MUC1 | ||||||||||
Synonyms | ADMCKD | ADMCKD1 | ADTKD2 | CA 15-3 | Ca15-3 | CD227 | EMA | H23AG | KL-6 | MAM6 | MCD | MCKD | MCKD1 | MUC-1 | MUC-1/SEC | MUC-1/X | MUC1/ZD | PEM | PEMT | PUM | ||||||||||
Gene Description | MUC1, mucin 1, cell surface associated, is a member of the mucin family of glycoproteins that provides a protective barrier from environmental factors in normal epitheliumm (PMID: 11192832, PMID: 27483328) and is involved in signaling during carcinogenesis and cancer progression (PMID: 34207342, PMID: 19935676). Hypoglycosylation and overexpression of MUC1 has been observed in different tumor types (PMID: 24667139, PMID: 27754373), including mesothelioma (PMID: 18454162), pancreatic ductal adenocarcinoma (PMID: 12379756), acute myeloid leukemia (PMID: 18640764), and breast carcinoma (PMID: 11391575). | ||||||||||
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