Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol MYC
Synonyms bHLHe39 | c-Myc | MRTL | MYCC
Gene Description MYC, MYC proto-oncogene, bHLH transcription factor, is a transcription factor that regulates expression of genes involved in cell cycle progression, apoptosis, cellular transformation (PMID: 25038584, PMID: 32071436) and the immune system (PMID: 29514782). Amplification, overexpression, and rearrangement of MYC is commonly observed in solid and hematological tumors (PMID: 28587062, PMID: 32203465), such as lung cancer (PMID: 32014901) and diffuse large B-Cell lymphoma (PMID: 32074595).
Additional content available in CKB BOOST