Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol NAB2
Synonyms MADER
Gene Description NAB2, NGFI-A binding protein 2, interacts with EGR proteins (1/2/3) to co-activate or co-repress gene transcription, and plays a role in regulation of T-cell function and in cellularity of the thymus (PMID: 28282643, PMID: 20506119, PMID: 17142725). A NAB2-STAT6 fusion has been associated with solitary fibrous tumor (PMID: 23313954, PMID: 23313952).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
4665 12 12q13.3 NM_005967 Tumor suppressor (PMID: 30606230)
Additional content available in CKB BOOST