Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene Symbol | NFATC3 | ||||||||||
Synonyms | n339260 | NF-AT4c | NFAT4 | NFATX | ||||||||||
Gene Description | NFATC3, nuclear factor of activated T cells 3, is a calcium responsive member of the NFAT family, which functions as a transcriptional activator and plays a role in cardiac development, vascular development, and thymic development (PMID: 25072963, PMID: 11983154). NFATC3 fusions with PLA2G15 have been identified in acute myeloid leukemia (PMID: 23251452), T-cell acute lymphocytic leukemia (PMID: 29330284), and colorectal cancer (PMID: 29909608). | ||||||||||
|