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Gene Symbol | NRAS | ||||||||||
Synonyms | ALPS4 | CMNS | KRAS | N-ras | NCMS | NRAS1 | NS6 | ||||||||||
Gene Description | NRAS, NRAS proto-oncogene, GTPase, is a member of the family of small GTPase that when activated by growth factors, stimulates multiple effector pathways such as RAF and PI3K to promote cell proliferation and survival (PMID: 29524560). NRAS mutations have been observed in a variety of cancers including melanoma, thyroid, breast, ovary cancer, and leukemia (PMID: 29524560, PMID: 30154648, PMID: 28860801). | ||||||||||
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