Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | NRF1 | ||||||||||
| Synonyms | ALPHA-PAL | ||||||||||
| Gene Description | NRF1, nuclear respiratory factor 1, is a transcription factor that regulates expression of genes involved in mitochondrial biogenesis and functions in cell-cycle progression (PMID: 30486409, PMID: 29149604) and cellular homeostasis (PMID: 30267745). Overexpression of Nrf1 has been observed in breast cancer (PMID: 30486409) and an NRF1-BRAF fusion has been reported in pleomorphic xanthoastrocytoma (PMID: 27624885). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
