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Gene Symbol DDR2
Synonyms MIG20a | NTRKR3 | TKT | TYRO10 | WRCN
Gene Description DDR2, discoidin domain receptor tyrosine kinase 2, is a tyrosine kinase receptor activated by collagen, promoting cell migration, proliferation, and survival (PMID: 22328973, PMID: 27398168). Altered expression and mutations of DDR2 have been identified in a variety of solid tumors, including ovarian (PMID: 27398168), lung (PMID: 28161936), gastric (PMID: 27350126), and HNSCC (PMID: 27434411).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
4921 1 1q23.3 NM_001014796 Oncogene (PMID: 30606230)
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