SLC67A1 - Gene Detail

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Gene Symbol SLC67A1
Synonyms BWR1A | BWSCR1A | HET | IMPT1 | ITM | ORCTL2 | p45-BWR1A | SLC22A18 | SLC22A1L | TSSC5
Gene Description SLC67A1 (SLC22A18), solute carrier family 67 member 1, encodes an organic cation transporter (PMID: 9744804) that is involved in lipid matabolism (PMID: 38626531, PMID: 30145211), tumor progression and drug resistance (PMID: 38366023, PMID: 30145211, PMID: 35411243). SLC67A1 mutations have been identified in Wilms’ tumor and lung cancer (PMID: 9751628), downregulation of Slc67a1 has been observed in colorectal cancer (PMID: 26196590) and glioma (PMID: 21936894, PMID: 22153794), and overexpression has been observed in non-small cell lung cancer (PMID: 22237119).
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