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Gene Symbol PAX5
Synonyms ALL3 | BSAP | PAX-5
Gene Description PAX5, paired box protein Pax-5, is a developmental transcription factor, which plays a role in B-cell development (PMID: 21970955). Pax5 fusions and mutations have been implicated in hematological malignancies (PMID: 22127921, PMID: 25428382), including B-lineage leukemia (PMID: 31381561, PMID: 30643249).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
5079 9 9p13.2 NM_016734 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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