Gene Detail
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| Gene Symbol | CDK18 | ||||||||||
| Synonyms | PCTAIRE | PCTAIRE3 | PCTK3 | ||||||||||
| Gene Description | CDK18, cyclin-dependent kinase 18, is a potential inhibitor of autophagy (PMID: 30289335) and plays a role in the DNA damage response by maintaining chromosome stability through ATR signalling (PMID: 30034634). Overexpression of Cdk18 has been associated with better prognosis of ER-negative breast cancer patients and response to chemotherapy (PMID: 30034634). | ||||||||||
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